Fujita, T.; Sato, K.; Suzuki, T.; Ikeuchi, K.; Tanino, K.
Two-step Transformation of Ketones to Carboxylic Acids Through a Ring-opening Reaction of Epoxynitriles with a Squarate Anion Chem. Lett. 2025, accepted.
Yoshitani, A.; Sasage, T.; Kato, R.; Suzuki, T.; Ikeuchi, K.; Tanino, K.
Remodeling of Tricyclic Carbon Frameworks with a Norbornene Scaffold Chem. Commun. 2025, 61, 16372-16375.
Kobayashi, M.; Ono, M.; Sasage, T.; Yamazaki, Y.; Suzuki, T.; Tanino, K.; Nakamura, S.; Kanoh, N.; Ikeuchi, K.
Synthesis of Cyclobuta[cd]pentalenes via an Intramolecular Double Michael Addition Reaction of 1,3-Cyclopentanedione Derivatives Org. Lett. 2025, 27, 9341-9346.
Yoshiki, M.; Koyama, S.; Kobayashi, H,; Mimura, S.; Ri, T.; Nishiyama, H.; Sasano, Y.; Iwabuchi, Y.; Fujimoto, J.; Kimishima, A.; Honsho, N,; Yokoe, H.; Ikeuchi, K.; Asami, Y.; Kanoh, N.
Design and Synthesis of a 3‑Arylenoyltetramic Acid Library Employing a Consecutive Three-Component Coupling J. Org. Chem. 2025, 90, 10338-10351.
2024
Watanabe, Y.; Haneda, T.; Kimishima, A.; Kuwae, A.; Suga, T.; Suzuki, T.; Iwabuchi, Y.; Honsho, M.; Honma, S.; Iwatsuki, M.; Matsui, H.; Hanaki, H.; Kanoh, N.; Abe, A.; Asami, Y.; Ōmura, S.
PurA is the main target of aurodox, a type III secretion system inhibitor Proc. Natl. Acad. Sci., U.S.A. 2024, 121(17), e2322363121. (Press Release in Japanese.)
2023
Tateishi, Y.; Sato, R.; Komatsu, S.; Noguchi, M.; Nagasawa, S.; Sasano, Y.; Kanoh, K.; Iwabuchi, Y.
Asymmetric Total Synthesis of Cytotrienin A: Late-stage Installation of C11 Side Chain onto the Macrolactam Scaffold Angew. Chem. Int. Ed.2023, 62, e20230314
Kanoh, N. Naturally occurring polyene macrolactams as pluripotent stem molecules: Their chemistry and biology, and efforts toward the creation of polyene macrolactam-based induced pluripotent small molecules (in Japanese) J. Synth. Org. Chem., Jpn.2022, 80, 817.
Segawa, R.; Takeda, H.; Yokoyama, T.; Ishida, M.; Miyata, C.; Saito, T.; Ishihara, R.; Nakagita, T.; Sasano, Y.; Kanoh, N.; Iwabuchi, Y.; Mizuguchi, M.; Hiratsuka, M.; Hirasawa, N.
A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins Biochem. Pharmacol. 2021, 194, 114819.
Tanaka, T.; Okuyama-Dobashi, K.; Motohashi, R.; Yokoe, H.; Takahashi, K.; Wiriyasermkul, P.; Kasai, H.; Yamashita, A.; Maekawa, S.; Enomoto, N.; Ryo, A.; Nagamori, S.; Tsubuki, M.; Moriishi, K.
Inhibitory Effect of a Novel Thiazolidinedione Derivative on Hepatitis B Virus Entry Antiviral Res. 2021, 194, 105165.
Kanoh, N.; Terajima, Y.; Tanaka, S.; Terashima, R.; Nishiyama, H.; Nagasawa, S.; Sasano, Y.; Iwabuchi, Y.; Nishimura, S.; Kakeya, H.
Toward the Creation of Induced Pluripotent Small (iPS) Molecules: Establishment of a Modular Synthetic Strategy to the Heronamide C-type Polyene Macrolactams and Their Conformational and Reactivity Analysis J. Org. Chem.2021, 86, 16231-16248; ChemRxiv 2021, DOI: 10.33774/chemrxiv-2021-947db.
Kanoh, N.; Terashima, R.; Nishiyama, H.; Terajima, Y.; Nagasawa, S.; Sasano, Y.; Iwabuchi, Y.; Saito, H.; Egoshi, S.; Dodo, K.; Sodeoka, M.; Pan, C.; Ikeuchi, Y.; Nishimura, S.; Kakeya, H.
Design, Synthesis and Antifungal Activity of 16,17-Dihydroheronamide C and ent-Heronamide C J. Org. Chem.2021, 86, 16249-16258; ChemRxiv 2021, DOI: 10.33774/chemrxiv-2021-278l6.
Okamura, T.; Koyamada, K.; Kanazawa, J.; Miyamoto, K.; Iwabuchi, Y.; Uchiyama, M.; Kanoh, N.
Synthetic access to gem-difluoropropargyl vinyl ethers and their application to propargyl Claisen rearrangement J. Org. Chem. 2021, 86, 1311-2036.(featured as the Supplementary Cover Picture.)
2020
Yokoe, H.; Mizumura, Y.; Sugiyama, K.; Yan, K.; Hashizume, Y.; Endo, Y.; Yoshida, S.; Kiriyama, A.; Tsubuki, M.; Kanoh, N.
Rapid access to dispirocyclic scaffolds enabled by diastereoselective intramolecular double functionalization of benzene rings Chem. Asian J. 2020, 15, 4271-4274. (featured in "Hot Topic: C-C Coupling"and as the Cover Picture.)
Takahashi, K.; Arai, Y.; Ikegami-Kawai, M.; Honda, T.
The formal synthesis of (+)-15-deoxy-Δ12,14-prostaglandin J2 by utilizing SmI2-promoted intramolecular coupling of bromoalkynes and α,β-unsaturated esters Tetrahedron2020, 76, 131148-131157.
2019
Okamura, T.; Fujiki, S.; Iwabuchi, Y.; Kanoh, N.
Gold(I)-catalyzed Nicholas reaction with aromatic molecules utilizing a bifunctional propargyl dicobalt hexacarbonyl complex Org. Biomol. Chem.2019, 17, 8522-8526 (featured as the front cover).
Okamura, T.; Egoshi, S.; Dodo, K.; Sodeoka, M.; Iwabuchi, Y.; Kanoh, N.
Highly chemoselective gem-difluoropropargylation of aliphatic alcohols Chem. Eur. J.2019, 25, 16002-16006.
Kanoh, N.; Kawamata-Asano, A.; Suzuki, K.; Takahashi, Y.; Miyazawa, T.; Nakamura, T.; Moriya, T.; Hirano, H.; Osada, H.; Iwabuchi, Y.; Takahashi, S.
An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s Sci. Rep.2019, 9, 18023.
Tougan, T.; Takahashi, K.; Ikegami-Kawai, M.; Horiuchi, M.; Mori, S.; Hosoi, M.; Horii, T.; Ihara, M.; Tsubuki, M.
In vitro and in vivo characterization of anti-malarial acylphenoxazine derivatives prepared from basic blue 3 Malaria J.2019, 18, 237.
Ishikawa, K.; Takahashi, K.; Hosoi, S.; Takeda, H.; Yoshida, H.; Wakana, D.; Tsubuki, M.; Sato, F.; Tojo, M.; Hosoe, T.
Antimicrobial agent isolated from Coptidis rhizome extract incubated with Rhodococcus sp. strain BD7100 J. Antibiot.2019, 72, 71-78.
Imai, M., Yokoe, H., Tsubuki, M., Takahashi, N.
Growth inhibition of human breast and prostate cancer cells by cinnamic acid derivatives and their mechanism of action Biol. Pharm. Bull.2019, 42, 1134–1139.
Before 2018 (Kanoh, N.)
Sasano, Y.; Koyama, J.; Yoshikawa, K.; Kanoh, N.; Kwon, E.; Iwabuchi, Y.
Stereocontrolled construction of ABCD tetracyclic ring system with vicinal all-carbon quaternary stereogenic centers of calyciphylline A type alkaloids Org. Lett.2018, 20, 3053-3056.
Uesugi, S.; Sasano, Y.; Matsui, S.; Kanoh, N.; Iwabuchi, Y. "Concise, protecting-group-free synthesis of (+)-nemonapride via Eu(OTf)3-catalyzed aminolysis of 3,4-epoxy alcohol Chem. Pharm. Bull.2017, 65, 22-24.
Morisaki, K.; Sasano, Y.; Koseki, T.; Shibuta, T.; Kanoh, N.; Chiou, W. H.; Iwabuchi, Y.
Nazarov cyclization entry to chiral bicyclo[5.3.0]decanoid building blocks and its application to formal synthesis of (-)-englerin A Org Lett2017, 19, 5142-5145.
Miyanaga, A.; Takayanagi, R.; Furuya, T.; Kawamata, A.; Itagaki, T.; Iwabuchi, Y.; Kanoh, N.; Kudo, F.; Eguchi, T.
Substrate recognition by a dual-function P450 monooxygenase GfsF involved in FD-891 biosynthesis Chembiochem2017, 18, 2179-2187.
Kanoh, N.; Okamura, T.; Suzuki, T.; Iwabuchi, Y.
A mild two-step propargylation of aromatic bioactive small molecules Org. Biomol. Chem.2017, 15, 7190 - 7195.
Nishiyama, Y.; Ohmichi, T.; Kazami, S.; Iwasaki, H.; Mano, K.; Nagumo, Y.; Kudo, F.; Ichikawa, S.; Iwabuchi, Y.; Kanoh, N.; Eguchi, T.; Osada, H.; Usui, T.
Vicenistatin induces early endosome-derived vacuole formation in mammalian cells Biosci. Biotech. Biochem.2016, 80, 902-910.
Kohyama, A.; Kanoh, N.; Kwon, E.; Iwabuchi, Y.
An enantiocontrolled entry to the tricyclic polar segment of (+)-fusarisetin A Tetrahedron Lett.2016, 57, 517-519.
Kohyama, A.; Fukuda, M.; Sugiyama, S.; Yamakoshi, H.; Kanoh, N.; Ishioka, C.; Shibata, H.; Iwabuchi, Y.
Reversibility of the thia-Michael reaction of cytotoxic C-5-curcuminoid and structure-activity relationship of bis-thiol-adducts thereof Org. Biomol. Chem.2016, 14, 10683-10687.
Kobayashi, H.; Sasano, Y.; Kanoh, N.; Kwon, E.; Iwabuchi, Y.
Total synthesis of the proposed structure of turkiyenine Eur. J. Org. Chem.2016, 270-273.
Kanoh, N.; Mano, K.; Saigusa, D.; Usui, T.; Iwabuchi, Y.
Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate Bioorg. Med. Chem. Lett.2016, 26, 5770-5772.
Kanoh, N.; Itoh, S.; Fujita, K.; Sakanishi, K.; Sugiyama, R.; Terajima, Y.; Iwabuchi, Y.; Nishimura, S.; Kakeya, H.
Asymmetric total synthesis of heronamides A-C: Stereochemical confirmation and impact of long-range stereochemical communication on the biological activity Chem. Eur. J.2016, 22, 8586-8595.
Kanoh, N.
Photo-cross-linked small-molecule affinity matrix as a tool for target identification of bioactive small molecules Nat. Prod. Rep.2016, 33, 709-718.
Itagaki, T.; Kawamata, A.; Takeuchi, M.; Hamada, K.; Iwabuchi, Y.; Eguchi, T.; Kudo, F.; Usui, T.; Kanoh, N.
Synthesis and structure-activity relationship study of FD-891: Importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells J. Antibiot.2016, 69, 287-293.
Uesugi, S.; Watanabe, T.; Imaizumi, T.; Ota, Y.; Yoshida, K.; Ebisu, H.; Chinen, T.; Nagumo, Y.; Shibuya, M.; Kanoh, N.; Usui, T.; Iwabuchi, Y.
Total synthesis and biological evaluation of irciniastatin A (a.k.a. psymberin) and irciniastatin B J. Org. Chem.2015, 80, 12333-12350.
Suzuki, T.; Okamura, T.; Tomohiro, T.; Iwabuchi, Y.; Kanoh, N.
Third generation photo-cross-linked small-molecule affinity matrix: A photoactivatable and photocleavable system enabling quantitative analysis of the photo-cross-linked small molecules and their target purification Bioconjugate Chem.2015, 26, 389-395.
Hirano, S.; Quach, H. T.; Watanabe, T.; Kanoh, N.; Iwabuchi, Y.; Usui, T.; Kataoka, T.
Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1 J. Antibiot.2015, 68, 417-420.
Hirano, S.; Quach, H. T.; Watahabe, T.; Kanoh, N.; Iwabuchi, Y.; Usui, T.; Kataoka, T.
Irciniastatin A induces a potent and sustained activation of extracellular signal-regulated kinase and thereby promotes ectodomain shedding of TNF receptor 1 in human lung carcinoma A549 cells Biol. Pharm. Bull.2015, 38, 941-946.
Uesugi, S.; Watanabe, T.; Imaizumi, T.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y. "Eu(OTf)3-catalyzed highly regioselective nucleophilic ring opening of 2,3-epoxy alcohols: An efficient entry to 3-substituted 1,2-diol derivatives Org. Lett.2014, 16, 4408-4411.
Takahashi, S.; Nagano, S.; Nogawa, T.; Kanoh, N.; Uramoto, M.; Kawatani, M.; Shimizu, T.; Miyazawa, T.; Shiro, Y.; Osada, H.
Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T J. Biol. Chem.2014, 289, 32446-32458.
Shibuta, T.; Sato, S.; Shibuya, M.; Kanoh, N.; Taniguchi, T.; Monde, K.; Iwabuchi, Y.
Enantioselective intramolecular aza-spiroannulation onto benzofurans using chiral rhodium catalysis Heterocycles2014, 89, 631-639.
Sakanishi, K.; Itoh, S.; Sugiyama, R.; Nishimura, S.; Kakeya, H.; Iwabuchi, Y.; Kanoh, N.
Total synthesis of the proposed structure of heronamide C Eur. J. Org. Chem.2014, 2014, 1376-1380.
Kanoh, N.; Kawamata, A.; Itagaki, T.; Miyazaki, Y.; Yahata, K.; Kwon, E.; Iwabuchi, Y.
A concise and unified strategy for synthesis of the C1-C18 macrolactone fragments of FD-891, FD-892 and their analogues: Formal total synthesis of FD-891 Org. Lett.2014, 16, 5216-5219.
Moriya, T.; Kawamata, A.; Takahashi, Y.; Iwabuchi, Y.; Kanoh, N
An improved fluorogenic NAD(P)+ detection method using 2-acetylbenzofuran: its origin and application Chem. Commun.2013, 49, 11500-11502.
Kanoh, N.; Suzuki, T.; Kawatani, M.; Katou, Y.; Osada, H.; Iwabuchi, Y.
Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning Bioconjugate Chem.2013, 24, 44-52.
Kanoh, N.; Ohno, Y.; Itagaki, T.; Fukuda, H.; Iwabuchi, Y.
On the origin of cine-substitution in the Stille coupling of trisubstituted iodoalkene and trans-vinylstannane Synlett2013, 24, 2660-2664.
Fukuda, H.; Nishiyama, Y.; Nakamura, S.; Ohno, Y.; Eguchi, T.; Iwabuchi, Y.; Usui, T.; Kanoh, N.
Synthesis and structure-activity relationship of vicenistatin, a cytotoxic 20-membered macrolactam glycoside Chem. Asian J.2012, 7, 2872-2881.
Takayama, H.; Takahashi, S.; Moriya, T.; Osada, H.; Iwabuchi, Y.; Kanoh, N.
Detection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surface ChemBioChem2011, 12, 2748-2752.
Takayama, H.; Moriya, T.; Kanoh, N.
Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules Chemical Genomics and Proteomics: Reviews and Protocols; Zanders, E. D., Ed.; Humana Press: Totowa, 2011, p 75-84.
Kawasumi, M.; Kanoh, N.; Iwabuchi, Y.
Concise entry to both enantiomers of 8-oxabicyclo[3.2.1]oct-3-en-2-one based on novel oxidative etherification: Formal synthesis of (+)-sundiversifolide Org. Lett.2011, 13, 3620-3623.
Kanoh, N.; Sakanishi, K.; Iimori, E.; Nishimura, K.; Iwabuchi, Y.
Asymmetric total synthesis of (–)-scabronine G via intramolecular double Michael reaction and Prins cyclization Org. Lett.2011, 13, 2864-2867.
Osada, H.; Kanoh, N.
Method of fixing low-molecular compound to solid-phase support
US Patent US 7713706 B2 (2010)
Yamakoshi, H.; Shibuya, M.; Tomizawa, M.; Osada, Y.; Kanoh, N.; Iwabuchi, Y.
Total synthesis and determination of the absolute configuration of (–)-idesolide Org. Lett.2010, 12, 980-983.
Yamakoshi, H.; Ohori, H.; Kudo, C.; Sato, A.; Kanoh, N.; Ishioka, C.; Shibata, H.; Iwabuchi, Y.
Structure-activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof Bioorg. Med. Chem.2010, 18, 1083-1092.
Yamakoshi, H.; Kanoh, N.; Kudo, C.; Sato, A.; Ueda, K.; Muroi, M.; Kon, S.; Satake, M.; Ohori, H.; Ishioka, C.; Ohshima, Y.; Osada, H.; Chiba, N.; Shibata, H.; Iwabuchi, Y.
KSRP/FUBP2 is a binding protein of GO-Y086, a cytotoxic curcumin analogue ACS Med. Chem. Lett.2010, 1, 273-276.
Watanabe, T.; Imaizumi, T.; Chinen, T.; Nagumo, Y.; Shibuya, M.; Usui, T.; Kanoh, N.; Iwabuchi, Y.
Syntheses and biological evaluation of irciniastatin A and the C1-C2 alkyne analogue Org. Lett.2010, 12, 1040-1043.
Sato, Y.; Fukuda, H.; Tomizawa, M.; Masaki, T.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y.
An enantio- and diastereocontrolled synthesis of (–)-salinosporamide A Heterocycles2010, 81, 2239-2246.
Kanoh, N.
Construction of photo-cross-linked microarrays of small molecules Small Molecule Microarrays: Methods and Protocols; Yao, S. Q., Uttamchandani, M., Eds.; Humana Press: Totowa, 2010, p 17-22.
Fukuda, H.; Nakamura, S.; Eguchi, T.; Iwabuchi, Y.; Kanoh, N.
Concise total synthesis of vicenistatin Synlett2010, 2589-2592.
Chinen, T.; Nagumo, Y.; Watahabe, T.; Imaizumi, T.; Shibuya, M.; Kataoka, T.; Kanoh, N.; Iwabuchi, Y.; Usui, T.
Irciniastatin A/psymberin induces JNK activation which involves caspase-8-dependent apoptosis via mitochondria pathway Toxicol. lett.2010, 199, 341-346.
Yamakoshi, H.; Ikarashi, F.; Minami, M.; Shibuya, M.; Sugahara, T.; Kanoh, N.; Ohori, H.; Shibata, H.; Iwabuchi, Y.
Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (–)-cylindrocyclophane A and its enantiomer, and implications for biological activity Org. Biomol. Chem.2009, 7, 3772-3781.
Sato, S.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y. "Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines Chem. Commun.2009, 6264-6266.
Sato, S.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y.
An expedient route to a potent gastrin/CCK-B receptor antagonist (+)-AG-041R J. Org. Chem.2009, 74, 7522-7524.
Miyazaki, I.; Okumura, H.; Simizu, S.; Takahashi, Y.; Kanoh, N.; Muraoka, Y.; Nonomura, Y.; Osada, H.
Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array Chembiochem2009, 10, 845-852.
Kanoh, N.; Osada, H.
Recent advances and developments of small molecule microarrays Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications; Osada, H., Ed.; Wiley: Hoboken, 2009, p 57-80.
Ikeda, S.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y.
Synthetic studies on daphnicyclidin A: Enantiocontrolled construction of the BCD ring system Org. Lett.2009, 11, 1833-1836.
Ichige, T.; Okano, Y.; Kanoh, N.; Nakata, M.
Total synthesis of methyl sarcophytoate, a marine natural biscembranoid J. Org. Chem.2009, 74, 230-243.
Shimizu, T.; Usui, T.; Fujikura, M.; Kawatani, M.; Satoh, T.; Machida, K.; Kanoh, N.; Woo, J. T.; Osada, H.; Sodeoka, M.
Synthesis and biological activities of reveromycin A and spirofungin A derivatives Bioorg. Med. Chem. Lett.2008, 18, 3756-3760.
Kawatani, M.; Okumura, H.; Honda, K.; Kanoh, N.; Muroi, M.; Dohmae, N.; Takami, M.; Kitagawa, M.; Futamura, Y.; Imoto, M.; Osada, H.
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I Proc. Natl. Acad. Sci. U.S.A.2008, 105, 11691-11696.
Kanoh, N.; Nakamura, T.; Honda, K.; Yamakoshi, H.; Iwabuchi, Y.; Osada, H.
Distribution of photo-cross-linked products from 3-aryl-3-trifluoromethyldiazirines and alcohols Tetrahedron2008, 64, 5692-5698.
Ikeda, S.; Shibuya, M.; Kanoh, N.; Iwabuchi, Y.
Efficient entry to the pyrroloquinoline core of Martinella alkaloids via novel base-catalyzed Mukaiyama-Mannich reaction Chem. Lett.2008, 37, 962-963.
Ichige, T.; Okano, Y.; Kanoh, N.; Nakata, M.
Total synthesis of methyl sarcophytoate J. Am. Chem. Soc.2007, 129, 9862-9863.
Woo, J. T.; Kawatani, M.; Kato, M.; Shinki, T.; Yonezawa, T.; Kanoh, N.; Nakagawa, H.; Takami, M.; Lee, K. H.; Stern, P. H.; Nagai, K.; Osada, H.
Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts Proc. Natl. Acad. Sci. U.S.A.2006, 103, 4729-4734.
Kanoh, N.; Kyo, M.; Inamori, K.; Ando, A.; Asami, A.; Nakao, A.; Osada, H.
SPR imaging of photo-cross-linked small-molecule arrays on gold Anal. Chem.2006, 78, 2226-2230.
Kanoh, N.; Asami, A.; Kawatani, M.; Honda, K.; Kumashiro, S.; Takayama, H.; Simizu, S.; Amemiya, T.; Kondoh, Y.; Hatakeyama, S.; Tsuganezawa, K.; Utata, R.; Tanaka, A.; Yokoyama, S.; Tashiro, H.; Osada, H.
Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions Chem. Asian J.2006, 1, 789-797.
Teruya, T.; Simizu, S.; Kanoh, N.; Osada, H.
Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells FEBS Lett.2005, 579, 2463-2468.
Kanoh, N.; Honda, K.; Simizu, S.; Muroi, M.; Osada, H.
Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics (vol. 44, p3559, 2005) Angew. Chem. Int. Ed.2005, 44, 4282-4282.
Kanoh, N.; Honda, K.; Simizu, S.; Muroi, M.; Osada, H.
Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics Angew. Chem. Int. Ed.2005, 44, 3559-3562.
Ichige, T.; Kamimura, S.; Mayumi, K.; Sakamoto, Y.; Terashita, S.; Ohteki, E.; Kanoh, N.; Nakata, M.
Synthetic studies on biscembranoids: Asymmetric total synthesis of methyl sarcoate Tetrahedron Lett.2005, 46, 1263-1267.
Woo, J.; Kawatani, M.; Kato, M.; Yonezawa, H.; Kanoh, N.; Shinki, T.; Takami, M.; Osada, H.; Stern, P.; Nagai, K.
Reveromycin A, which induces apoptosis specifically in functional osteoclasts, inhibits bone resorption in vitro and in vivo J. Bone. Miner. Res.2004, 19, S417-S417.
Usui, T.; Watanabe, H.; Nakayama, H.; Tada, Y.; Kanoh, N.; Kondoh, M.; Asao, T.; Takio, K.; Watanabe, H.; Nishikawa, K.; Kitahara, T.; Osada, H.
The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin Chem. Biol.2004, 11, 799-806.
Ichige, T.; Miyake, A.; Kanoh, N.; Nakata, M.
Oxidative deprotection of 1,3-dithiane group using NaClO2 and NaH2PO4 in aqueous methanol Synlett2004, 1686-1690.
Terauchi, T.; Terauchi, T.; Sato, I.; Shoji, W.; Tsukada, T.; Tsunoda, T.; Kanoh, N.; Nakata, M.
Formal total synthesis of altohyrtin C (spongistatin 2). Part 1: Aldol approach to unite AB and CD spiroacetals Tetrahedron Lett.2003, 44, 7741-7745.
Terauchi, T.; Tanaka, T.; Terauchi, T.; Morita, M.; Kimijima, K.; Sato, I.; Shoji, W.; Nakamura, Y.; Tsukada, T.; Tsunoda, T.; Hayashi, G.; Kanoh, N.; Nakata, M.
Formal total synthesis of altohyrtin C (spongistatin 2). Part 2: Construction of fully elaborated ABCD and EF fragments Tetrahedron Lett.2003, 44, 7747-7751.
Smith, A. B., III; Kanoh, N.; Ishiyama, H.; Minakawa, N.; Rainier, J. D.; Hartz, R. A.; Cho, Y. S.; Cui, H.; Moser, W. H.
Tremorgenic indole alkaloids. The total synthesis of (–)-penitrem D J. Am. Chem. Soc.2003, 125, 8228-37.
Kanoh, N.; Tomatsu, A.; Nishikawa, T.; Ide, M.; Tsuchida, T.; Isshiki, K.; Nakata, M
Practical deracemization of NM-3, a synthetic angiogenesis inhibitor Tetrahedron-Asymm.2003, 14, 1251-1253.
Kanoh, N.; Kumashiro, S.; Simizu, S.; Kondoh, Y.; Hatakeyama, S.; Tashiro, H.; Osada, H.
Toward the construction of universal small-molecule microarrays: functional group independently-immobilized arrays of small molecules Biomolecular Chemistry: A Bridge for the Future; the scientific committee of ISBC 2003, Ed.; Maruzen: Tokyo, 2003, p 330-331.
Kanoh, N.; Kumashiro, S.; Simizu, S.; Kondoh, Y.; Hatakeyama, S.; Tashiro, H.; Osada, H.
Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions Angew. Chem. Int. Ed.2003, 42, 5584-5587.
Fukuzaki, T.; Kobayashi, S.; Hibi, T.; Ikuma, Y.; Ishihara, J.; Kanoh, N.; Murai, A.
Studies aimed at the total synthesis of azadirachtin. A modeled connection of C-8 and C-14 in azadirachtin Org. Lett.2002, 4, 2877-2880.
Terauchi, T.; Morita, M.; Kimijima, K.; Nakamura, Y.; Hayashi, G.; Tanaka, T.; Kanoh, N.; Nakata, M.
Synthetic studies on altohyrtins (spongistatins): Synthesis of the C29-C44 (EF) portion Tetrahedron Lett.2001, 42, 5505-5508.
Yamamoto, Y.; Ishihara, J.; Kanoh, N.; Murai, A.
Synthetic studies on azadirachtin: An efficient asymmetric synthesis of the highly functionalized tricyclic decalin part of azadirachtin Synthesis2000, 1894-1906.
Terauchi, T.; Terauchi, T.; Sato, I.; Tsukada, T.; Kanoh, N.; Nakata, M.
Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15-C28 (CD) spiroacetal portion Tetrahedron Lett.2000, 41, 2649-2653.
Smith, A. B., III; Kanoh, N.; Ishiyama, H.; Hartz, R. A.
Total synthesis of (–)-penitrem D" J. Am. Chem. Soc.2000, 122, 11254-11255.
Kanoh, N.; Ishihara, J.; Yamamoto, Y.; Murai, A.
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